EesⓘEnd-Systolic Elastance (Contractility) Slope of the ESPVR line. Reflects intrinsic LV contractility independent of loading conditions. Higher = stronger contraction.
2.5mmHg/mL
EaⓘArterial Elastance (Afterload) Lumped measure of total arterial load on the LV. Integrates SVR, arterial compliance, and heart rate. Higher = more afterload.
1.8mmHg/mL
EDVⓘEnd-Diastolic Volume (Preload) LV volume at end of diastole. Determined by venous return and LV compliance. Higher = more preload (Frank-Starling mechanism).
125mL
BⓘChamber Stiffness (Diastolic) Exponent of the EDPVR curve. Higher = stiffer ventricle = steeper diastolic pressure rise. Elevated in HFpEF, concentric LVH, constriction.
0.025mL-1
HRⓘHeart Rate Affects cardiac output (CO = SV x HR) and contributes to arterial elastance. Does not change the PV loop shape directly but alters CO and Ea.
70bpm
V0ⓘUnstressed Volume Volume-axis intercept of the ESPVR. The theoretical LV volume at zero pressure. Shifts the entire PV loop left or right. Increased in DCM/eccentric remodeling.